To start using your Trezor device, go to trezor.io/start. Begin by downloading the Trezor Suite, available for Windows, macOS, and Linux. After installation, follow the on-screen prompts to set up your Trezor wallet securely. Connect your Trezor device to your computer using the USB cable provided, then initialize and backup your device as instructed. Once set up, you can manage your cryptocurrencies, perform transactions, and access additional features offered by Trezor Suite. Ensure to keep your recovery seed phrase safe, as it's crucial for restoring access to your funds in case your device is lost or damaged.